The Pitttsburgh Xplosion had a successful season, but fell to Bellingham in the second round of the playoffs after an almost three week layoff. The Xplosion left for the CBA following the 2005-2006 season.
| Date | Opponent | Score |
|---|---|---|
| 10/30 | Indiana | L 116-109 |
| 11/9 | Lake Erie | L 116-112 |
| 11/15 | @ Detroit | W 105-102 |
| 11/16 | @ Detroit | W 105-96 |
| 11/25 | Kentucky | W 121-116 |
| 11/27 | @ Indiana | L 128-105 |
| 11/30 | Detroit | L 107-93 |
| 12/2 | Toledo | W 114-112 |
| 12/7 | Lake Erie | W 147-132 |
| 12/8 | @ Toledo | L 135-124 |
| 12/9 | @ Detroit | L 108-94 |
| 12/11 | @ Indiana | L 131-116 |
| 12/12 | Toledo | W 121-102 |
| 12/15 | Lake Erie | W 148-106 |
| 12/20 | Ohio | W 163-116 |
| 12/22 | @ Lake Erie | W 150-123 |
| 1/6 | Ohio | W 170-97 |
| 1/8 | Lake Erie | W 152-117 |
| 1/15 | @ Kentucky | W 113-112 |
| 1/17 | Indiana | L 122-116 |
| 1/21 | @ Toledo | W 112-99 |
| 1/22 | @ Indiana | L 111-89 |
| 1/24 | Kentucky | W 129-117 |
| 1/28 | @ Maryland | L 122-96 |
| 2/1 | Ohio | W 162-92 |
| 2/14 | Indiana | L 131-119 |
| 2/17 | Toledo | W 126-110 |
| 2/20 | Toledo | W 144-121 |
| 2/28 | Maryland | W 111-108 |
| Playoffs | ||
| 3/18 | Bellingham | L 122-115 |